The Main Active Chemical Alkaloids In Kratom

The Main Active Chemical Alkaloids In Kratom

Kratom, a plant native to Southeast Asia, has become increasingly popular as an alternative to traditional painkillers. It contains various active compounds, each with different effects on the body. This blog will explore the primary active compounds found in kratom.

The Main Active Chemical Alkaloids In Kratom

Mitragynine is a naturally occurring alkaloid found in the leaves of kratom. It is the primary active compound in kratom and is responsible for many of its effects. Mitragynine is structurally similar to other alkaloids found in plants of the Rubiaceae family, such as yohimbine and voacangine. Mitragynine stimulates and activates specific receptors in the brain, producing analgesic and euphoric effects. It has been known to help with alleviating pain. However, it also has stimulating effects at lower doses, making it a popular traditional medicine in Southeast Asia, where it has been used for centuries to alleviate fatigue and increase productivity.

7-hydroxymitragynine is another active alkaloid found in kratom, though in smaller amounts. It is said to be responsible for many of kratom’s pain-relieving effects. However, it is more potent than Mitragynine and may cause some negative side effects, such as nausea and dizziness.

Mitraphylline is an alkaloid in kratom that has anti-inflammatory and immune-boosting effects. It may also increase energy levels and focus slightly.

Speciogynine is believed to have muscle relaxant and anti-inflammatory properties and may contribute to the plant’s pain-relieving effects.

Paynantheine has mild pain-relieving effects and can reduce muscle tremors and spasms.

Ajmalicine is an alkaloid found in kratom that has anti-adrenergic effects, reducing blood pressure and heart rate. It may also have mild sedative properties.

The Main Active Chemical Alkaloids In Kratom

In conclusion, kratom contains multiple active compounds that can have various effects on the body. Mitragynine and 7-hydroxymitragynine are the primary alkaloids responsible for some possibly helping relieve pain.  Meanwhile, mitraphylline, speciogynine, paynantheine, and ajmalicine may also contribute to the overall effects of kratom. However, more research is needed to fully understand how these compounds interact with the body and the potential risks they pose.